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von Willebrand factor (VWF) (/ ˌ f ʌ n ˈ v ɪ l ɪ b r ɑː n t /) is a blood glycoprotein involved in hemostasis.It is deficient and/or defective in von Willebrand disease and is involved in many other diseases, including thrombotic thrombocytopenic purpura, Heyde's syndrome, and possibly hemolytic-uremic syndrome. Increased plasma levels in many cardiovascular, neoplastic, and. La enfermedad de von Willebrand (EvW) es la anomalía en la coagulación de carácter hereditaria más común entre los humanos, aunque también puede ser adquirida como consecuencia de otras enfermedades. Se debe a una deficiencia cualitativa o cuantitativa del factor de von Willebrand (FvW), una proteína multimérica requerida para la adhesión y agregación plaquetaria De von willebrandfactor is een stollingseiwit dat betrokken is bij bloedstolling.Het eiwit is genoemd naar de Finse arts Erik Adolf von Willebrand (1870-1949).. Als een bloedvat beschadigd raakt, komt er een proces op gang dat bloedstolling wordt genoemd. Hierbij zijn bloedplaatjes (trombocyten) betrokken, maar ook ongeveer 20 stollingseiwitten, waaronder het belangrijke eiwit von. Doença de von Willebrand é uma doença hemorrágica, hereditária causada por uma diminuição ou uma disfunção da proteína chamada de fator de von Willebrand (FvW). Isto ocorre devido à mutação no cromossomo 12 e é caracterizada por deficiência qualitativa ou quantitativa do fator de von Willebrand

Von Willebrand factor - Wikipedi

A von Willebrand-Jürgens-szindróma vagy von Willebrand-betegség (angolul: von Willebrand disease) az embereknél leírt leggyakoribb veleszületett véralvadási rendellenesség; ugyanakkor, más kóros állapot is előidézheti. A von Willebrand-faktor (vWF) minőségi vagy mennyiségi hiányossága idézi elő. A von Willebrand-faktor egy multimer fehérje, amely a trombocita. La maladie de Willebrand aussi appelée maladie de von Willebrand ou syndrome de Willebrand, une maladie hémorragique constitutionnelle ().Elle touche les deux sexes. Il s'agit en réalité d'un ensemble de maladies qui ont comme point commun une anomalie quantitative ou qualitative du facteur Willebrand.. Elle touche 1 à 5 individus sur 10 000 [1].. Von Willebrandin tauti (vWD) on periytyvistä verenvuototaudeista yleisin. Tauti johtuu von Willebrand -tekijän (vWF) puutoksesta tai vajauksesta. Se vaikuttaa veren kykyyn hyytyä kunnolla. Verenvuoto voi sen takia kestää pitkään ja olla erittäin runsasta. Muita tyypillisiä oireita ovat mustelmat, runsaat kuukautiset ja nenän, suun ja silmien verenvuodot von Willebrand är en svensk-finsk adelsätt, introducerad vid Riddarhuset under nummer 1834. [1].Ätten har tidigare haft en friherrlig gren (nr.344), vilken dog ut 2 november 1859 då friherre Ernst Magnus von Willebrand dog barnlös. [ Types of Von Willebrand Disease: Pathophysiology: Therapy: Procedures: Type 1: Low levels of all proteins: Desmopressin: Desmopressin Responsive: Infuse 0.3 ug/kg to end 45 minutes before procedure. May repeat every 24 hours. For major procedures follow factor VIII levels with plan to keep troughs over 80% Not desmopressin responsive

Enfermedad de von Willebrand - Wikipedia, la enciclopedia

Il fattore di von Willebrand (vWF) è uno dei fattori che interagiscono nella cascata biochimica della coagulazione.. Chimicamente è una glicoproteina dal peso molecolare di circa 250 kD che circola nel plasma sotto forma di multimeri a basso, intermedio ed alto peso molecolare. È sintetizzato dalle cellule endoteliali e dai megacariociti e va incontro a processi di dimerizzazione e. Choroba von Willebranda (łac. morbus von Willebrandi, ang. von Willebrand disease, vWD) - choroba charakteryzująca się skłonnością do krwawień samoistnych lub po urazach (operacja, uderzenie itp.). Występuje w postaci ciężkiej, umiarkowanej i lekkiej. Przyczyną jej jest brak we krwi czynnika von Willebranda odpowiedzialnego za adhezję płytek do miejsca uszkodzenia naczynia i. Description. Le facteur de von Willebrand est un multimère constitué de deux sous-unités identiques [3] mais peut être présent sous forme de monomères plus ou moins étirés, ce qui en modifie ses propriétés [4].. Le récepteur au VWF sur le thrombocyte est appelé Gp-1b-IX-V (Gp pour glycoprotéine).. Le facteur de von Willebrand est synthétisé par Bosson von Willebrand (s. 1940), radio- ja televisiotoimittaja ja kriitikko, Bo von Willebrandin poika Carl-August von Willebrand (1923-1999), opettaja, kääntäjä Erik Adolf von Willebrand (1870-1949), professori, von Willebrandin taudin löytäj Vid von Willebrands sjukdom orsakar brist på von Willebrands faktor (ett protein) i blodet att det får svårt att levra sig. Dels orsakar brist på von Willebrands faktor att blodplättarna har svårt att binda samman (primär hemostas), men vW-faktorn är även viktig som en hjälpfaktor till faktor VIII (sekundär/humoral hemostas). Sjukdomen drabbar - till skillnad mot hemofili A och.

Von willebrandfactor - Wikipedi

Von Willebrand disease (vWD) is the most common hereditary blood-clotting disorder in humans. An acquired form can sometimes result from other medical conditions. [1] It arises from a deficiency in the quality or quantity of von Willebrand factor (vWF), a multimeric protein that is required for platelet adhesion.As well as humans, it is known to affect several breeds of dogs Inherited von Willebrand disease (VWD) is the most common inherited bleeding disorder. Acquired von Willebrand syndrome (aVWS; acquired deficiency or dysfunction of von Willebrand factor [VWF]), however, is much less common, and the diagnosis is not often suspected in a bleeding patient von Willebrand disease (uncountable) An hereditary disease, characterized by a tendency to hemorrhage, and caused by a defect in blood platelet activity. This latter point is of concern given the high prevalence of von Willebrand disease (1 in 100 individuals) in the United States. - N. A. Goldenberg, L. Jacobson and M. J. Manco-Johnson

Factorul von Willebrand este o glicoproteină plasmatică sintetizată de celulele endoteliale și megacariocite, care circulă în sânge și se atașează la suprafețele endoteliale lezate facilitând aderența trombocitelor și joacă, în plus, rolul de transportor plasmatic al factorului VIII ⁠(d), de care se leagă necovalent.Rolul său fiziologic este de importanță majoră în. Von Willebrand disease is a blood clotting disorder. It is the most common genetic clotting disorder. It occurs in about one in one hundred people, although only one in one hundred of those will actually show serious symptoms. It can also be acquired as a secondary complication of other diseases, most commonly aortic valve stenosis, which leads to an immune response against the clotting factor. VIII:C = antihemofíliás globulin (az X-kromoszóma kódolja) vWF = von Willebrand - faktor (autoszomális kromoszóma kódolja) A VIII:C faktort a máj endothelsejtjei és a megakaryocyták termelik. Nélkülözhetetlen a plazma eredetű alvadáshoz a X faktor aktiválása révén. A vWF megvédi a VIII-as faktort az inaktiválástól, és. A surname .··Ellipsis of von Willebrand disease Definition from Wiktionary, the free dictionar Erik Adolf von Willebrand (1 February 1870 - 12 September 1949) was a Finnish physician who made major contributions to hematology. Von Willebrand disease and von Willebrand factor are named after him. He also researched metabolism, obesity and gout, and was one of the first Finnish physicians to use insulin to treat a diabetic coma

Doença de von Willebrand - Wikipédia, a enciclopédia livr

La maladie de Willebrand aussi appelée maladie de von Willebrand ou syndrome de Willebrand, une maladie hémorragique constitutionnelle ().Elle touche les deux sexes. Il s'agit en réalité d'un ensemble de maladies qui ont comme point commun une anomalie quantitative ou qualitative du facteur Willebrand.. Elle touche 1 à 5 individus sur 10 000 [1].. El gen que codifica la síntesis de la unidad de factor von Willebrand se halla en el cromosoma 12. La deficiencia de este factor es conocida como enfermedad de Von Willebrand.Además, el factor de von Willebrand está involucrado en un gran número de patologías diferentes, como la púrpura trombocitopénica trombótica, el síndrome de Heyde y posiblemente el síndrome hemolítico-urémico

Willebrand-Jürgens-Syndrom - Wikipedi

Factor de von Willebrand - Wikipedia, la enciclopedia libr

Video: Von Willebrandův faktor - Wikipedi

Von-Willebrand-Faktor - Wikipedi

Von Willebrands faktor, ofte forkortet vWF, er et hemostaseprotein som dannes i karveggens endotelceller og i blodplater. Proteinet sørger for adhesjon mellom sårkanten i skadet vev og aktiverte blodplater ved at den binder kollagenet i det skadede vevet til glykoprotein Ib på blodplaten. I tillegg er den transportfaktor for koagulasjonsfaktor VIII, og sørger for at denne ikke blir offer. عامل فون ويل براند (بالإنجليزية: Von Willebrand factor)‏ هو عبارة عن سلسلة من بروتين سكري متعدد، وهو كبير نسيباً بالنسبة لعوامل تخثر الدم الأخرى، ويتم تصنيع عامل فون ويل براند في الصفائح الدموية والأنسجة الاندوثيلية المكونة.

Von Willebrand nr 1834 Från Adelsvapen-Wiki. Adliga och friherrliga ätterna von Willebrand nr 1834 och 344. Adlad 1676-04-15, introd. 1731. En gren friherrlig 1806-08-08 (ej introd.) och åter 1812-07-14 enl. 37 § R.F., introd. 1814. Utdöd 1859-11-02 It arises from a qualitative or quantitative deficiency of von Willebrand factor (vWF) a multimeric protein that is required for platelet adhesion. It is known to affect humans and dogs (notably Doberman Pinschers) and rarely swine cattle horses and cats

Malattia di von Willebrand - Wikipedi

Czynnik von Willebranda, VWF (z ang. von Willebrand factor) - niezbędny składnik krwi biorący udział w procesie jej krzepnięcia, duża glikoproteina zbudowana z kilku podjednostek kodowanych przez gen położony na chromosomie 12. Czynnik von Willebranda jest niezbędny dla adhezji płytek do kolagenu w miejscu uszkodzonego naczynia. We krwi łączy się z czynnikiem VIII, chroniąc go. Von Willebrand factor (vWF) The normal physiology of von Willebrand's factor can be understood as follows: Structure. It is a glycoprotein present in blood and is involved in hemostasis. Its synthesis takes place in the endothelium (in the Weibel-Palade bodies), megakaryocytes (α-granules of platelets), and subendothelial connective tissue

Acquired von Willebrand disease is a rare bleeding disorder that might be caused by other medical problems or medicines. It prevents blood from clotting properly. It is rarer than the inherited form of von Willebrand disease. Medical problems that might cause acquired von Willebrand disease include Biografie. Erik von Willebrand wurde als Kind finnlandschwedischer Eltern im damals zum Russischen Kaiserreich gehörenden Großfürstentum Finnland geboren. Er studierte an der Universität Helsinki Medizin, wo er 1896 zum Arzt approbiert und 1899 mit der Arbeit Zur Kenntnis der Blutveränderungen nach Aderlassen. Eine experimentelle Studie. promoviert wurde Von Willebrand's Disease Symptoms and Treatments in Dogs - Von Willebrand's disease (vWD) is the most common inherited bleeding disorder in dogs. It has been described in more than 50 breeds. Clotting disorders are caused by an absence of one of the coagulation factors needed to complete the clotting sequence Chemical compound and disease context of VWF. A novel mutation, R1308L (3923G > T) was present in the heterozygous state in five members of a family with type 2B von Willebrand disease (VWD) characterized by a full set of von Willebrand factor (VWF) multimers in plasma and by the absence of thrombocytopenia before and after desmopressin (DDAVP) .; The interaction of the glycoprotein (GP) Ib-IX.

Von Willebrand disease, type 3: Introduction. Von Willebrand disease, type 3: A rare inherited blood coagulation disorder characterized by a defect in plasma protein called the von Willebrand factor which leads to bleeding problems. Type 3 is the most severe form of von Willebrand Disease. More detailed information about the symptoms, causes, and treatments of Von Willebrand disease, type 3 is. von Willebrand protein is also a carrier protein for Factor 8 = if it is not working properly you have decreased factor 8 as well. Prevalence = up to 1/100 (1%) of the population Characteristics - VARY even in families Easy bruising is the major problem Recurrent nosebleeds Heavy menstrual cycles Bleeding after surger Der Von-Willebrand-Faktor wird von Gefäßendothelzellen, die einen Teil der perivaskulären Matrix darstellen, synthetisiert und sezerniert. Er fördert die Phase der Thrombozytenadhäsion durch die Bindung an einen Rezeptor auf der Thrombozytenoberfläche (Glykoprotein Ib/IX), wodurch die Thrombozyten mit der Gefäßwand verbunden werden. Der vWF ist darüber hinaus notwendig, um normale. Von Willebrand factor (vWF or VWF) is a protein that is one of several components of the coagulation system that work together, and in sequence, to stop bleeding within the body. VWF testing measures the amount of the protein present in blood and determines how well the protein functions Von Willebrand factor (vWF) (/ˌfʌnˈvɪlɪbrɑːnt/) is a blood glycoprotein involved in hemostasis. It is deficient or defective in von Willebrand disease and is involved in a large number of other diseases, including thrombotic thrombocytopenic purpura, Heyde's syndrome, and possibly hemolytic-uremic syndrome. Increased plasma levels in a large number of cardiovascular, neoplastic, and.

Von Willebrand factor - Wikipedia

von Willebrand hastalığı (vWH) en yaygın kalıtsal kanama bozukluğudur. 1/800-1/1000 sıklıkta oluşur.. von Willebrand faktör (vWF) iki ana fonksiyonu olan bir plazma glikoproteinidir.. Yüksek damar duvarı basıncında trombositlerin damar duvarına yapışmalarını kolaylaştırı To find out if a person has von Willebrand disease (VWD), the doctor will ask questions about personal and family histories of bleeding. The doctor also will check for unusual bruising or other signs of recent bleeding and order some blood tests that will measure how the blood clots Inhibition of von Willebrand factor-dependent platelet function by increased platelet cyclic AMP and its prevention by cytoskeleton-disrupting agents. Coller, B.S. Blood (1981) Cell type-specific regulation of von Willebrand factor expression by the E4BP4 transcriptional repressor

Von Willebrand-Jürgens-szindróma - Wikipédi

Von Willebrand factor is a blood glycoprotein involved in hemostasis.It is deficient and/or defective in von Willebrand disease and is involved in many other diseases, including thrombotic thrombocytopenic purpura, Heyde's syndrome, hemolytic-uremic syndrome.Increased plasma levels in many cardiovascular and connective tissue diseases are presumed to arise from adverse changes to the. Von Willebrand disease (VWD) is the most common inherited bleeding disorder. Von Willebrand factor helps blood platelets form clumps and stick to the blood vessel wall, which is essential in the normal blood clotting process. Von Willebrand disease is caused by a deficiency of von Willebrand factor Von Willebrand disease is the most common hereditary blood-clotting disorder in humans. An acquired form can sometimes result from other medical conditions, it arises from a deficiency in the quality or quantity of von Willebrand factor, a multimeric protein, required for platelet adhesion. As well as humans, it is known to affect several breeds of dogs; the three forms of vWD are: hereditary.

Maladie de Willebrand — Wikipédi

  1. Von Willebrand factor תסמינים דימום , דימום מהאף , דימום פנימי , hemorrhagic disease , המטומה , hemarthrosis , דימום מדרכי העיכול , דימום מוחי , דימום מוחי תת-עכביש
  2. Von Willebrand factor testing is done to investigate excessive or recurrent bleeding episodes or a personal or family history of excessive bleeding. Testing is used to help diagnose Von Willebrand disease and distinguish between the various types of VWF. Two types of tests may be required: VWF.
  3. 1 Definition. Der von-Willebrand-Faktor, kurz vWF, ist ein Glykoprotein, das zwei wichtige Funktionen in der Hämostase erfüllt. Er initiiert die Thrombozytenadhäsion und schützt den Faktor VIII vor Proteolyse.Er wird meist als Gerinnungsfaktor bezeichnet, im engeren Sinne ist diese Bezeichnung aber nicht korrekt, da vWF nicht an der Gerinnungskaskade teilnimmt

Rarely, von Willebrand disease can develop later in life in people who didn't inherit an abnormal gene from a parent. This is known as acquired von Willebrand syndrome, and it's likely caused by an underlying medical condition. Risk factors. Autosomal dominant inheritance pattern Open pop-up dialog box La malaltia de Von Willebrand (MvW) és la malaltia hereditària més comuna de trastorn de la coagulació que es descriu en els éssers humans, encara que també pot ser adquirit com a resultat d'altres situacions mèdiques. S'origina en una deficiència qualitativa o quantitativa de factor de von Willebrand (FvW), una proteïna multimèrica que es requereix en l'adhesió de les plaquetes Von Willebrands sykdom er den mest vanlige arvelige koaguleringssykdommen som er beskrevet hos mennesker. Den ble beskrevet første gang av Erik Adolf von Willebrand i 1926. Den kan også forekomme hos hunder El factor de von Willebrand (FvW) és una glicoproteïna de la sang que participen en l'hemostàsia. És deficient o defectuosa en la malaltia de von Willebrand i està involucrat en un gran nombre d'altres malalties, com la púrpura trombocitopènica trombòtica, la síndrome de Heyde, i, possiblement, en la síndrome hemolíticourèmica. L'augment dels nivells plasmàtics en un gran nombre.

Von Willebrand factor antigen. This determines the level of von Willebrand factor in your blood by measuring a particular protein. Von Willebrand factor activity. There are a variety of tests to measure how well the von Willebrand factor works in your clotting process A structural explanation for the antithrombotic activity of ARC1172, a DNA aptamer that binds von Willebrand factor domain A1. Structure. 2009 Nov 11;17(11):1476-84. PMID: 19913482 doi: 10.1016/j.str.2009.09.01 Genealogy for Adam von Willebrand (1728 - 1758) family tree on Geni, with over 200 million profiles of ancestors and living relatives. People Projects Discussions Surname

francuski: (1.1) maladie de Willebrand, maladie de von Willebrand, syndrome de Willebrand łaciński: (1.1) morbus von Willebrandi niemiecki: (1.1) Willebrand-Jürgens-Syndro Von Willebrandova bolest (vWB) je najčešći nasljedni poremećaj zgrušavanja krvi (koagulacije) u čovjeka, do kojega dolazi zbog kvantitativnog ili kvalitativnog nedostatka Von Willebrandova faktora (vWF). VWF je mulitmerični protein koje je nužan za adheziju trombocita.Postoje četiri tipa nasljedne vWB, a bolest može biti i stečena. Bolest je dobila naziv po finskom liječniku Erik. Von Willebrand factor, glycoprotein that plays an important role in stopping the escape of blood from vessels following vascular injury. Von Willebrand factor works by mediating the adherence of platelets to one another and to sites of vascular damage. Learn more about its actions and deficiency in disease

Von Willebrand factor type A domain - Wikipedia

Von Willebrand disease (VWD) is a disorder that makes it hard for your blood to clot. This happens because you don't have enough of a clotting protein called von Willebrand factor (VWF). It. The acquired von Willebrand syndrome (AVWS) is a bleeding disorder that is frequently unrecognized or is misdiagnosed as von Willebrand disease. AVWS is characterized by structural or functional defects of von Willebrand factor (VWF) that are secondary to autoimmune, lymphoproliferative or myeloproliferative, malignant, cardiovascular, or other. VONVENDI ® [von Willebrand factor (Recombinant)]: created specifically to treat VWD 1 The first and only recombinant von Willebrand factor (VWF) 2 VONVENDI is used to treat VWD, an inherited bleeding disorder that makes it difficult to form blood clots. 3 VONVENDI can be used in two ways 1:. To treat and control bleeding episodes as needed, or on-demand The level of factor VIII may also be lower than normal. This is the mildest and most common form of the disease. About 3 out of 4 people diagnosed with von Willebrand disease have type 1. Type 2. In type 2 von Willebrand disease, a defect in von Willebrand factor causes it to not work properly. Type 2 is divided into 2A, 2B, 2M, and 2N Hemophilia, von Willebrand disease, other coagulopathies If hemophiliac, replace factor before LP; CT Before Lumbar Puncture. LP without CT is likely safe if: History Age < 60; Not immunocompromised; No history of CNS disease; No seizure within 1 week of presentation; Physical Exam No altered level of consciousnes

Von Willebrand disease | Wiki | EveripediaVon Willebrand -tekijä – Wikipedia

Erik Adolf von Willebrand (Vaasa, 1 februari 1870 - Pernå, 12 september 1949) was een Fins arts en anatoom.Hij was tevens professor aan de Universiteit van Helsinki.In 1926 beschreef hij als eerste een bloedstollingsziekte, die later de ziekte van von Willebrand zou worden genoemd. Ook de von willebrandfactor is naar hem genoemd Enfermedad de Von Willebrand.Es un trastorno hereditario que afecta a la capacidad de la sangre para coagularse adecuadamente. Debe su nombre al doctor Erik von Willebrand, que fue quien describió la enfermedad por primer vez en 1926.Como grupo, los trastornos de la coagulación (como la hemofilia) son muy poco frecuentes Von Willebrand disease (VWD) is a common inherited bleeding disorder in the general population affecting males and females equally, but women may be disproportionately impacted due to the bleeding challenges of menstruation and childbirth. There are three main types of VWD (VWD type 1, VWD type 2, and VWD type 3) each with differing degrees of.

Further reading Edit. Leissinger C, Becton D, Cornell C Jr, Cox Gill J. High-dose DDAVP intranasal spray (Stimate) for the prevention and treatment of bleeding in patients with mild haemophilia A, mild or moderate type 1 von Willebrand disease and symptomatic carriers of haemophilia A. Haemophilia 2001;7:258-66.PMID 11380629 la le facteur de von Willebrand (VWF) est l'un des facteurs qui interagissent dans la biochimie de la cascade de coagulation.. Chimiquement, il est glycoprotéine de poids moléculaire d'environ 250 kD qui circule dans plasma sous la forme de multimères à bas, moyen et haut poids moléculaire. Il est synthétisé à partir les cellules endothéliales et mégacaryocytes et subit des processus. Erik Adolf von Willebrand (Vaasa, 1. veljače 1870. - Pernaja, 12. rujna 1949.), finski liječnik ().. Von Willebrand je rođen u gradu Vaasa, a medicinu je diplomirao 1896.g. na sveučilištu u Helsinkiju.Tijekom svog života i rada najviše se bavio istraživanjem svojstava krvi i koagulacijom.. Von Willebrand je prvi opisao poremećaj zgrušavanja krvi, koji je kasnije dobio po njemu naziv. Just explaining a little bit about von Willebrand's and what medicines I take. articles that explains Von Willebrand Disease http://en.m.wikipedia.org/wiki/Von_Wi..

Von Willebrandin tauti - Wikipedi

  1. or Willebrands may refer to: * Von Willebrand disease, a hereditary coagulation abnormality disease * Von Willebrand factor, a blood glycoprotein involved in hemostasis * Erik Adolf von Willebrand, a Finnish internist * Julia Willebrand, a
  2. La faktoro de von Willebrand (en angla, vWF) estas glukoproteino de la sango kiu intervenas en la dekomenca momento de la hemostazio. Ĝia funkcio, kun la fibronektino estas permesi ke la platetoj kuniĝu stabile al la surfaco. La geno kiu kodigas la sintezon de la unueco de faktoro de von Willebrand estas en la kromosomo 12
  3. Die Von Willebrand-Krankheit, auch als Angiohämophilie oder von-Willebrand-Jürgens-Syndrom bekannt, ist eine häufige, erbliche hämorrhagische Erkrankung. Sie ist durch Mutationen charakterisiert, die zu einer Abnahme der Spiegel oder einer Beeinträchtigung in der Aktivität des Von-Willebrand-Faktors (VWF) führen. Von-Willebrand-Krankheit (Von-Willebrand-Syndrom): Mehr zu Symptomen.
  4. I. 개요 . 폰 빌레브란트 병(von Willebrand Disease)은 핀란드 내과의사인 Erik von Willebrand가 1926년에 처음 확인한 병으로, 혈장, 혈소판, 혈관 내피세포 등에서 발견되는 부착 당단백인 폰 빌레브란트 인자(von Willebrand factor, VWF)의 결핍 또는 기능저하 에 의해 혈소판과 혈관 사이의 상호작용이 저해되어.
  5. Von Willebrand disease type 2 is characterized by qualitative deficiency and functional anomalies of von Willebrand factor. It is divided in different subtypes including 2A, 2B, 2M and 2N (Normandy variant). The mutant VWF protein in types 2A, 2B and 2M are defective in their platelet-dependent function, whereas the mutant protein in type 2N is.
  6. It is a highly sensitive way to screen patients for von Willebrand factor defect. 17,18 Plasma von Willebrand factor antigen was measured by immunoturbidimetry, and factor VIII coagulant activity.
  7. Von Willebrand disease is a type of clotting disorder - more common than the better known haemophilia. A specific protein is missing from the blood so that injured blood vessels cannot heal in the usual way. Von Willebrand disease is named after the doctor first described the condition in the early 20th Century. This page from Great Ormond Street Hospital (GOSH) explains the causes, symptoms.
File:1ao3 Human Von Willebrand Factor A3 Domain

von Willebrand - Wikipedi

  1. La ĉi-suba teksto estas aŭtomata traduko de la artikolo Von Willebrand factor article en la angla Vikipedio, farita per la sistemo GramTrans on 2016-05-25 14:44:05. Eventualaj ŝanĝoj en la angla originalo estos kaptitaj per regulaj retradukoj. Se vi volas enigi tiun artikolon en la originalan Esperanto-Vikipedion, vi povas uzi nian specialan redakt-interfacon
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File:1ao3 Human Von Willebrand Factor A3 Dong02Erik Adolf von Willebrand - Wikipedia
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